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Document Type

Original Article

Abstract

Background: Diabetes mellitus problems lead to diabetes retinopathy (DRP) and diabetic macular edoema (DME), two retinal disorders.

Aim of the study: the study designed to assess effectiveness of intravitreal ranibizumab injections versus intravitreal ranibizumab injections only in with macular edoema diabetics.

Patients and Methods:

Interventional randomized prospective trial, whereas 80 diabetic macular edoema eyes

shared and equally distributed to double collections, each collection includes 40 eyes and the first collection injected by ranibizumab intravitreal on 3 times, while the second exposed to two sessions of adjuvant micropulse diode laser therapy along with one intravitreal injection of ranibizumab.

Results: After the cure, the best corrected visual accuity increased significantly. Further research found that in diabetic individuals with macular edoema whom got ranibizumab plus laser therapy, visual accuity at 3 and 6 months of follow-up was remarkably greater than visual acuity before treatment.

Conclusion: Ranibizumab intravitreal applications only had a better impact on reducing diabetic macular edoema than ranibizumab intravitreal injections also including a micro-pulse laser diode.

Keywords

VEGF inhibitor, ranibizumab, intravitreal injection, diabetic macular edoema, and micro-pulse diode laser

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