Document Type

Original Article


Background: Keratoconus is one of ectatic corneal disease which is marked by central corneal scarring, apical corneal thinning, visual impairment, and corneal steepening. Its exact etiology is unknown. Aim and objectives: to assess the depth of the corneal stromal demarcation line (A measure of the depth of the cross-linking therapy into the stroma is thought to exist in the transition zone between the treated anterior corneal stroma and the untreated posterior corneal stroma) 6

after conventional crosslinking versus accelerated crosslinking after one and three months postoperative. Subjects and methods: In Cairo, Egypt's Kobri El Qobba Military Specialized Eye Hospital, this prospective, randomized, comparative, cross-sectional research was carried out. The 40 eyes with progressive keratoconus used in this research were split into two groups, each of which had 20 eyes: group 1: 20 eyes had accelerated cross-linking, and group 2: 20 eyes had conventional (standard) cross-linking. Results: The demarcation line and Kmax at 1-month and 3-months postoperative showed no statistically substantial variation between the two study groups. Conclusion: A safe and effective therapy for advancing keratoconus is cross-linking. At all times, rapid CXL was equivalent to traditional CXL, and both types of CXL considerably increased CCT and demarcation line depth.


Conventional Cross-Linking; Corneal Stromal Depth; Demarcation Line