Endometrial Thickness (Compaction) and Serum Progesterone Level on the Day of Thawed Frozen Embryo Transfer as a Predictor of Early Reproductive Outcomes

Authors

Ismael Mohamed Talaat EL Garhy, Obstetrics & Gynecology Department, Faculty of Medicine Al- Azhar University, Cairo , Egypt.
Mohamed Shehata AbdEl Aal, Assisted Reproduction Unit, International Islamic Center for Population Studies & Researches Al- Azhar University, Cairo , Egypt.
Ashraf Taha Abd Elmouttaleb, Assisted Reproduction Unit, International Islamic Center for Population Studies & Researches Al- Azhar University, Cairo, Egypt.
Islam Ahmed Rammah, Assisted Reproduction Unit, International Islamic Center for Population Studies & Researches Al- Azhar University, Cairo, Egypt.Follow

Document Type

Original Article

Abstract

Background: The majority of studies have found that the thin endometrium during in vitro fertilization (IVF) therapy has a negative impact on pregnancy outcomes and that levels of serum progesterone may affect the pregnancy outcomes. The study's primary aim was to investigate any potential associations between the clinical pregnancy rate and serum progesterone levels on the day of the transfer of frozen embryos. Our study's secondary endpoint involved using transvaginal ultrasonography (TVUS) on the day of the transfer of frozen embryos to determine if endometrial compaction is related to increased rates of pregnancy.

Aim: The Primary aim of the study was to investigate the possible relationship between level of serum progesterone concentrations on the day of frozen embryo transfer and clinical pregnancy rate,while secondary end-point of our study was to investigate whether endometrial compaction is associated with increased pregnancy rates using Transvaginal ultrasonography (TVUS) on the day of frozen embryo transfer.

Patients and Methods: Our study included 120 women who underwent frozen-thawed embryo transfer during the period from August 2021 until April 2022. They were selected according to inclusion criteria: age (20–39 years), primary or secondary infertility, and undergoing FET regardless of the cause of the freezing of the embryos (supernumerary embryos obtained after transfer of a fresh embryo, elective embryo freezing due to ovarian hyperstimulation syndrome, or other causes).

Result: We demonstrated that endometrial compaction isn't linked to statistically significant enhancements in biochemical or clinical pregnancy, and that serum levels of P4 at or over 10 ng/mL on the day of FET aren't linked to statistically significant enhancements in either.
Conclusion: On the day of the frozen embryo transfer, endometrial compaction and levels of serum progesterone did not show any clinically significant improvement in the biochemical or clinical pregnancy rates.

Keywords

Endometrial thickness ; Serum Progesterone; Frozen Embryo Transfer.

Subject Area

Obstetrics and Gynecology

How to Cite This Article

Garhy, Ismael Mohamed Talaat EL; Aal, Mohamed Shehata AbdEl; Elmouttaleb, Ashraf Taha Abd; and Rammah, Islam Ahmed (2023) "Endometrial Thickness (Compaction) and Serum Progesterone Level on the Day of Thawed Frozen Embryo Transfer as a Predictor of Early Reproductive Outcomes," Al-Azhar International Medical Journal: Vol. 4: Iss. 12, Article 40.
DOI: https://doi.org/10.58675/2682-339X.2167