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Document Type

Original Article

Abstract

Objectives: The purpose of this investigation is to assess the relationship between electrocardiographic ST-T changes and coronary artery disease (CAD) and coronary lesions in individuals with increased LVMI.

Methods: This retrospective cohort study was conducted on one hundred and sixty patients with elevated LVMI (LVMI >115 g/m2 in males and 95 g/m2 in females), patients with hypertrophic cardiomyopathy (HOCM), patients with cardiac amyloidosis, individuals with aortic stenosis (AS) and individuals with athletic myocardial hypertrophy undergoing coronary angiography. Participants were splitted into two groups. Group I: 80 individuals with increased LVMI and positive strain pattern. Group II: 80 individuals with increased LVMI and no strain pattern.

Results: ST-T changes were significant predictors of significant/non-significant coronary angiography lesion T-wave inversion was the highest predictor (AUC: 0.726, p

Conclusions: Electrocardiographic ST-T changes (T-wave inversion, down slopping depression, and to a lesser degree horizontal depression) can be used as significant predictors for significant/non-significant CAD angiographic lesions in patients with increased LVMI.

Keywords

Coronary Artery, Increased Left Ventricular Mass Index, Strain pattern

Subject Area

Cardiovascular

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