Document Type
Original Article
Abstract
Background: Subclinical hypothyroidism (SCH) is distinguished by an elevated TSH but normal levels of free triiodothyronine (FT3) and free thyroxine (FT4) (FT4). In terms of pregnancy outcomes, levothyroxine has been linked to improvement in several studies.
Aim and objectives: Is to evaluate the treatment influence of levothyroxine therapy on the health of the fetus in pregnant women who have subclinical hypothyroidism.
Subjects and methods: This case-control research was performed in Obstetrics and Gynecology department in Al-Hussein and Sayed Galal Hospitals, Al-Azhar University, Started from October 2022 to April 2023. There were two sets of women involved: Group (A) (Case group): Patients were subjected to levothyroxine therapy. Group (B) (Control group): Patients were not subjected to levothyroxine therapy (take placebo).
Result: When comparing groups A and B, there was no significant distinction in the outcomes or complications experienced by the mothers in group B. The incidence of low birth weight and Group B had a far greater rate of low-Apgar scores than Group A did. Nonetheless, the frequency of unfavorable infant outcomes and Group B had more difficulties than Group A, although the difference was not clinically meaningful.
Conclusion: The current study indicated that the rate of low birth weight and low Apgar score might be affected by levothyroxine administration.
Keywords
Subclinical hypothyroidism; Thyroid hormones; Triiodothyronine; Thyroxine.
Subject Area
Obstetrics and Gynecology
How to Cite This Article
Mostafa, Taher Mohamed; Abdel-Aziz, Bassem Ragab; and Atta, Alsayed Omar Alsayed
(2023)
"Pregnancy outcomes in women with subclinical hypothyroidism Treated with Levothyroxine,"
Al-Azhar International Medical Journal: Vol. 4:
Iss.
11, Article 35.
DOI: https://doi.org/10.58675/2682-339X.2121
