•  
  •  
 

Corresponding Author

Mohammed Fares Ibrahim Elnahas

Document Type

Original Article

Abstract

Background: The danger of respiratory diseases in the newborn, such as respiratory distress syndrome, is increased when the mother chooses to have the baby before 39 weeks of gestation through an elective caesarean section. Prostaglandins are helpful for the developing lungs because they stimulate the release of the stress hormone catecholamines, which in turn increases the production of the protective molecule surfactant. Nonetheless, the efficacy of antenatal preventive injections of prostaglandin is still debatable in clinical practice.

Aim of the study: to assess the effectiveness of vaginal misoprostol in preventing transitory tachypnea in newborns prior to elective caesarean section.

Patients and methods: As a whole, 140 pregnant females who were listed to have an elective caesarean section at Al-Hussien University Hospital were recruited during antenatal care visits for this prospective randomized clinical research. They were split into two teams: The cases were separated into two groups: Group I (misoprostol group; n = 70) contained females who were given a misoprostol vaginal tablet of 50 mcg immediately prior to their elective caesarean section, and cases were divided into Group II (no misoprostol group; n = 70), which consisted of women who were not given misoprostol.

Result: In comparison to the control groups, the vaginal misoprostol group saw a significantly lower incidence of tachypnea in newborns.

Conclusion: Ultimately, prophylactic vaginal misoprostol prior to elective CS at 37–39 weeks of gestation decreases the rate of neonatal respiratory morbidity and may be an effective method to inhibit neonatal tachypnea in newborns.

Keywords

misoprostol, cesarean section, tachypnea, newborn

Subject Area

Obstetrics and Gynecology

Download

Share

COinS