Evaluation of Transvaginal Sonographic Elastography in Differentiating Endometrial Hyperplasia from Endometrial Carcinoma in Perimenopausal Women

Authors

Hany Mohamed Abd El-Mo’ty Hussin Allawy, Obstetrics and Gynecology Department, Nasr City Health Insurance Hospital, Cairo, EgyptFollow
Hossam Al-Din Hussein Kamel, Obstetrics and Gynecology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
Ahmed Mohamed Fathallah Al-Sheikh, Obstetrics and Gynecology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
Emad Mohamed Adel Ibrahim Elkady, Diagnostic and Interventional Radiology Department, International Medical Center, Cairo, Egypt

Document Type

Original Article

Abstract

Background: It is noticed that 70 % of gynecological complaint in the peri and postmenopausal women is abnormal uterine bleeding, so it is a considerable issue. This study aimed to assess the value of transvaginal sonographic elastography in differentiating endometrial hyperplasia from endometrial carcinoma. Patients and methods: It is a prospective study, applied on patients with perimenopausal bleeding over 2 years duration between April 2020 and April 2022. We applied this study on 72 women; the mean age of endometrial carcinoma group was 50.11±1.27, 46.77±2.75 for typical endometrial hyperplasia group, 48.36±2.42 for atypical endometrial hyperplasia group and the control group was 47.76±2.57. The comparison between strain index values by transvaginal sonographic elastography in each group were done by a one-way analysis of variance (ANOVA) and Post Hoc test: Tukey's test. Results: The mean value of strain index was 10.9±3.72 in endometrial carcinoma group, 2.73±1.70 in endometrial hyperplasia group and 1.01±0.19 in control group with a statistically significant higher mean value of strain index in endometrial carcinoma group followed by endometrial hyperplasia group and the control group is the lowest one, with p-value (p5.4 is considered as a cut-off value characterizing endometrium carcinoma from endometrial hyperplasia, with sensitivity 88.9% and specificity 85.7%. Conclusion: Transvaginal sonographic elastography is a beneficial tool in differentiating between endometrial hyperplasia and endometrial cancer.

Keywords

Elastography; Endometrium; Sonography; Carcinoma.

Subject Area

Obstetrics and Gynecology

How to Cite This Article

Allawy, Hany Mohamed Abd El-Mo’ty Hussin; Kamel, Hossam Al-Din Hussein; Al-Sheikh, Ahmed Mohamed Fathallah; and Elkady, Emad Mohamed Adel Ibrahim (2023) "Evaluation of Transvaginal Sonographic Elastography in Differentiating Endometrial Hyperplasia from Endometrial Carcinoma in Perimenopausal Women," Al-Azhar International Medical Journal: Vol. 4: Iss. 11, Article 24.
DOI: https://doi.org/10.58675/2682-339X.2118