Document Type
Original Article
Abstract
Background: The incidence of chronic kidney disease (CKD) is rising globally, and there are raised proofs connecting (SDB) with kidney diseases. Those proofs are attributed to increased upper airway resistance in such patients leading to a disturbed sleeping rhythm.
Aim of the work: To evaluate the incidence, severity, and patterns of SDB and related nocturnal hypoxia amongst people with advanced CKD, hemodialysis & healthy individuals.
Patient and Methods: This case-control research was performed in the Departments of Chest Diseases & nephrology unit at Al-Azhar University hospitals from January 2022 to December 2022. The study involved 60 participants diagnosed as CKD, either on regular follow-up in outpatients’ clinics or attending to hemodialysis unit. Twenty participants who appeared to be in good health served as a control group.
Results: The occurrence of SDB in CKD patients was (81.7%) and detected sleep apneas were predominantly obstructive. Severe obstructive sleep apnea (OSA) was frequent among different CKD patients. Significant strong positive correlation of periodic limb movement with serum K+ level was found. Moreover, significant good negative correlations of apnea-hypopnea index with estimated glomerular filtration rate (eGFR) and urea concentration were noticed. blood urea, serum creatinine and eGFR are independent variables associated with severe OSA.
Conclusion: SDB are frequently overlooked by renal healthcare providers. Severe OSA and nocturnal hypoxia are highly prevalent amongst advanced CKD & HD cases.
Keywords
sleep-disordered breathing (SDB), hemodialysis (HD)
Subject Area
Chest
How to Cite This Article
Elyazid, Hussein Ahmed Abu; Basiony, Fareed Shawky; Ayoub, Hazem Sayed Ahmed; and Hwary, Abd Allah Mohamed Aly El
(2023)
"Sleep Disordered Breathing in Patients with Chronic Kidney Diseases,"
Al-Azhar International Medical Journal: Vol. 4:
Iss.
11, Article 22.
DOI: https://doi.org/10.58675/2682-339X.2112
