Document Type
Case Series
Abstract
Background: Preeclampsia is a condition that develops after 20 weeks of pregnancy and may manifest as late as 4-6 weeks after delivery. It is characterized by extensive vascular endothelial dysfunction and vasospasm.
Aim and objectives: This study's primary objective was to analyze the maternal and perinatal outcomes in pre-eclampsia (PE) in relation to serum albumin levels. Subjects and methods: This prospective observational cohort research was carried out at Hussein Hospital, Al-Azhar University's department of obstetrics and gynecology. Between August September and March 2022, cases were recruited from the emergency unit. 100 severe preeclamptic women were included in the trial, and they were split into two groups according on their blood albumin levels. Group I PE with an albumin level of >25 g/L (mild hypoproteinemia [MHP]) and group II PE with an albumin level of ≤ 25 g/L (severe hypoproteinemia [SHP]).
Results: preterm birth, fetal growth restriction, and NICU admission were significantly more common in SHP group compared to MHP group. Poor maternal and neonatal outcomes were significantly more common in SHP group compared to MHP group.
Conclusion: Estimation of albumin levels in pregnancy is of value in the early prediction of preeclampsia. SHP PE warrants careful monitoring throughout pregnancy due to its increased risk of unfavorable maternal and newborn outcomes compared to MHP PE.
Keywords
Albumin; Hypoproteinemia; Fetal Growth Restriction; Pre-Eclampsia; Pregnancy
How to Cite This Article
Zakaria, Abdelmoniem Mohamed; ELboghdady, Adel Aly; and Hamouda, Mahmoud Riad Anwar
(2023)
"Association of hypo-proteinemia in pre-eclampsia with maternal and peri-natal outcomes,"
Al-Azhar International Medical Journal: Vol. 4:
Iss.
1, Article 6.
DOI: https://doi.org/10.58675/2682-339X.1619
