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Corresponding Author

Mahmoud Ragab Ashour

Document Type

Case Series

Abstract

Background: The most prevalent congenital disorders affecting children are cleft lip and palate. By restoring skin tissue and texture, platelet-rich plasma has been demonstrated in the study to be a good treatment for muscle damage, and chronic wounds, including atrophic and contractile scars. Aim and objectives: Objectives to examine the effects of platelet-rich plasma (PRP) on aesthetic results and scar formation after unilateral cleft lip restoration. Subjects and methods: Thirty patients (12 female as well as 18 male) with a complete unilateral cleft lip were chosen from the outpatient clinic of the Department of Cosmetic Procedures, Faculty of Medicine, Al-Azhar University facilities to participate in this research, which was a randomized control clinical trial. Result: The control group's mean scar width measured by ultrasonography at six months was 4.96 0.929 mm and the study group was 3.8 0.886 mm, respectively. As a result, there was a statistically significant difference between the two groups' mean scar widths as determined by ultrasonography. Figure 3 shows that the scar was considerably less in the study group than in the control group at both the first point (0.8310.231mm compared to 1.490.442mm; P0.00) and the second point (1.0150.103mm versus 2.2750.984; P0.00). The research group's mean VSS at one month was 3.7921.054, whereas the control group's was 5.7080.656. Conclusion In addition to reducing the formation of scar tissue, autologous PRP treatment promoted the healing of cutaneous and muscle wounds.

Keywords

Cleft Lip; Platelet Rich Plasma; Scar

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