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Corresponding Author

Saleh Abd Elsalam Ibrahem Algazzar

Document Type

Original Article

Abstract

Background: Oliguria or A rise in serum creatinine concentration have been performed to detect acute kidney injury (AKI), however none of these methods is

sensitive. Some Pediatrics researches used Renal Angina Index (RAI) to predict AKI is beneficial.

Aim and objectives: evaluation the Renal Angina Index efficacy in identifying critically sick individuals whom were more prone to get severe AKI.

Subjects and methods: 50 diseased patients were hospitalized in ICUs and participated in this prospective observational research. Subjected to clinical examination and laboratory tests for blood urea, serum creatinine, CBC , Ast, Alt, Albumin, electrolytes, levels of serum calcium, phosphorus, sodium, and potassium. All patients were tested for urinary L-FABP upon ICU admission. RAI was determined.

Results: The average age of studied patients was 48.6 ± 13 years, 31 patients were males (62%). The average BMI was 29.4 ± 4.6 kg/m². AKI was presented in 31 patients (62%), 14 patients of them (45.2%) were of grade I AKI and 17 patients (54.8%) were of grade III AKI. There is increased urinary L-FABP in patients with AKI (14 ± 1.8) when compared with individuals without AKI (8.6 ± 1.0). and increased RAI in patients with AKI (21.4 ± 13) when compared with individuals without AKI (6.2 ± 7.4).

Conclusion: DM, HTN, elevated WBCs, and CKD were the most frequent risk factors for AKI. Patients with AKI had higher levels of urine L-FABP compared to those without AKI, and those with AKI had statistically significantly higher RAI than those without AKI.

Keywords

Renal Angina Index, Acute Kidney Injury, Intensive Care Unit

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