Document Type
Original Article
Abstract
Introduction&Aim of the work: to assess the effects of smoking on TAC and NO levels in seminal plasma of patients who suffer from oligoasthenozoospermia.
Patient and Methods: this study was conducted on ninety males with age range 20-40 years. They were classified into two groups. Group (A) 45 Smoker with oligoasthenozoospermia and Group (B) 45 non- Smoker with oligoasthenozoospermia. this research was between January 2017 and May 2018. Semen sample will be collected and examined for, Parameters of semen will be considered according to (WHO, 2010). Hormonal profile (FSH, LH, Testosterone, Prolactin). Seminal plasma level of nitrite as a surrogate to nitric oxide. Seminal plasma level of total antioxidant capacity (TAC).
Results:
Statistical analysis showed significant increase of Nitric oxide in group (A) more than group (B) (P-value < 0.05) and significant decrease of Total antioxidants (uuM/L) in group (A) more than group (B) (P-value < 0.05) with oligoasthenozoospermia. It showed negative correlation between nitric oxide level and total antioxidants capacity level
conclusions:
smoking has an obvious effect on fertility, specifically normal morphology of sperm and sperm motility. This effect most probably due to oxidative stress as a result of smoking.
Keywords
Antioxidant; Nitric oxide; oligoasthenozoospermia; smoking
How to Cite This Article
Abdelwahed, Abdelshakour A.; Abdelazez, Hassan M.; Aboumohamed, Nagah Mohamed; and Elazeem, Mohamed M. Abd
(2023)
"Nitric Oxide Level and Total Antioxidant Capacity in the Seminal Plasma of Infertile Smoking Men,"
Al-Azhar International Medical Journal: Vol. 4:
Iss.
1, Article 22.
DOI: https://doi.org/10.58675/2682-339X.1641
