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Corresponding Author

Mohammed Hassan Hussien Hassan

Document Type

Case Series

Abstract

Background: Diabetes may cause a wide range of eye disorders, including cataracts, glaucoma and other ocular abnormalities, recurrent styes, non-arteritic anterior ischemic optic neuropathy and diabetic papillopathy.

Objective: OCT angiography will be utilized to examine the capillaries of the retina in diabetic retinopathy patients with non-proliferative disease.

Patients and methods: This is a prospective cross-section clinical study that was carried out on 60 eyes of 34 subjects, divided into; Group A; 30 eyes of 19 patients with different stages of NPDR, and Group B; 30 eyes of 15 healthy subjects with normal healthy eyes as control, all subjects were selected from patients attending the outpatient ophthalmology clinic of (Memorial Institute of Ophthalmic Research), between December 2020 and December 2021.

Results: As a result of the sugar profile, the duration of DM ranged from 8 to 25 years, with an average of 12 years. The FBS and HbA1c values in the cases group were significantly higher than in the control groups. Renal function and lipid profile did not vary significantly between groups of patients and controls. As far as eye exams were concerned, there was no difference between the patients and controls (BCVA, UCVA and IOP).

Conclusion: In the macular region, choriocapillaris flow areas significantly reduced in patients with NPDR, moreover, choriocapillaris blood flow affected by HbA1c, suggesting that patients with NPDR and poor glycemic control may have significant impairment of choriocapillaris blood flow.

Keywords

Choroid; Non Proliferative Diabetic Retinopathy; OCTA.

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