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Corresponding Author

Abo Sayed, Mustafa

Document Type

Original Article

Abstract

Background: Anemia, electrolyte disturbances and mineral bone disorders are common outcomes of chronic kidney disease (CKD). We aimed to asses relationship between anemia and mineral bone disorder (MBD) parameters in stages 3-5 CKD on conservative treatment patients. Results: The study revealed a statistically significant association between Hb and eGFR, and also showed a statistically significant negative relationship (p value = 0.001) (r = -0.38) between Hb and serum creatinine. It also revealed a semi-inverse relationship between serum parathormone (iPTH) and hemoglobin level in blood between CKD. Whenever there is an increase in the serum iPTH reflects the decrease in the level of hemoglobin in the blood of the study sample of patients with chronic kidney disease. One of the important statistical results indicated by the study is that blood phosphate is linked to low hemoglobin in kidney patients. Our study agreed with studies that show that vitamin D deficiency is closely related to low hemoglobin level in CKD patients. The higher the calcium level, the lower the hemoglobin level. We found that increased blood calcium is associated with a lower hemoglobin level. Conclusion: Our study showed the significant association between CKD-BMD and anemia. It also showed that increased serum phosphate, parathyroid activity, severe deficiency in vitamin D and a high incidence of anemia among patients with chronic kidney disease.

Keywords

Anemia; Chronic Kidney Disease; Mineral bone disorder

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