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Corresponding Author

Alhamshary, Mahamad

Document Type

Case Series

Abstract

Background: Suppressing hormone hyper-secretion, lowering tumour mass, preserving normal pituitary function, minimizing long-term effects from excess hormone production, and preventing tumour recurrence are all aims of pituitary tumour treatment. Objectives: The purpose of this study was to detect the pituitary gland during pituitary surgery in order to remove as much tumour as possible while preserving pituitary function and minimizing postoperative complications. Methods: From June 2019 to November 2021, this study was done at the Neurosurgery Departments of Al-Azhar University Hospitals "Al-Hussein" and "Bab El-Sheria," and the 6th of October Hospital for Health Insurance. In this study, a total of 30 participants with a pituitary single lesion who had trans-sphenoidal surgery were analyzed and evaluated for preoperative, intraoperative, and postoperative factors. Preoperative and intraoperative gland tissue identification, operational issues, resection degree, and postoperative hormone deficiency were all taken into account. Results: Only 4.76 percent (1 out of 21) of individuals with healthy pituitary gland tissue required postoperative hormone replacement. In the nine cases where intraoperative gland tissue identification failed, postoperative hormone replacement was necessary in 66.67 percent (6 out of 9) of the cases. On postoperative MRI, 66.67 percent of patients had radical tumour excision, whereas 33.33 percent of patients (10) had tumour remnants. According to the findings, endoscopic trans-sphenoidal surgery can locate and retain pituitary gland tissue and function. After surgery, normal pituitary function is predicted if the gland tissue is preserved.

Keywords

Pituitary gland; Preservation of hormones; Trans-sphenoidal endoscopy

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