Prevalence and severity of mineral bone disorders in chronic kidney disease patients

Authors

Mohamed Eid Mohamed, مستشفي الحسين الجامعيFollow
Ahmed Alaa-Eldin Saad, Internal Medicine department, Faculty of Medicine, Al-Azhar University, EgyptFollow
Alsayed Rashed, Department of Internal Medicine, Faculty of Medicine, Al Azhar University, CairoFollow
Hatem Abdallah, Rheumatology and Rehabilitation department, Faculty of Medicine, Al-Azhar University, EgyptFollow
mohamed abo-ghabha, Clinical Pathology Department, Faculty of Medicine, Al-Azhar University, EgyptFollow

Corresponding Author

Eid Mohamed, Mohamed

Abstract

Background Bone abnormalities are frequently developed in hemodialysis patients and people with chronic kidney disease (CKD). It results from aberrant bone turnover and a decline in bone mineral density (BMD). Aim and objectives: With the help of dual energy X-ray absorptiometry in this study, poor bone mineral density in CKD patients at Al-Hussein University Hospital will be analysed for prevalence and severity. Subjects and methods: This Cross-Sectional research included 120 Patients (2 groups) 60 CKD Patients and 60 Hemodialysis Patients. The study has been conducted in Nephrology Unit Al-Hussien University Hospital. Results: In ESRD group there was Significant statistically (p-value = 0.008) T score femur and eGFR had a positive connection (r = 0.34). Significant statistically (p-value = 0.008) There is an r-value of 0.34 between the T score of the spine and the eGFR. While in CKD group significantly significant (p-value = 0.001) differences. T score femur and Creat have a negative connection (r = -0.41) with each other. Significant statistically (p-value = 0.001) T score femur and eGFR had a positive connection (r = 0.43). Significant statistically (p-value = 0.02) The T score forearm and the eGFR have a positive connection (r = 0.3). Conclusion: MBD are common features among CKD patients especially in late stages leading to Osteoporosis and fractures. Dual Energy X- Ray (DXA) could be utilized as efficient method for detection of the level of bone affliction in CKD patients and is essential for bone loss monitoring Keywords: mineral bone disorders, chronic kidney diseases.

Article Type

Original Article

Keywords

prevalence; mineral bone disorders; chronic kidney diseases

How to Cite This Article

Eid Mohamed, Mohamed; Saad, Ahmed Alaa-Eldin; Rashed, Alsayed; Abdallah, Hatem; and abo-ghabha, mohamed (2022) "Prevalence and severity of mineral bone disorders in chronic kidney disease patients," Al-Azhar International Medical Journal: Vol. 3: Iss. 12, Article 15.
DOI: https://doi.org/10.21608/aimj.2023.164028.2186