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Corresponding Author

Abu Zaid, Waleed

Document Type

Original Article

Abstract

Background: Diabetes mellitus has been linked to altered mineral and trace element metabolism, which may play a unique role in the development and progression of this illness. Aim and objectives: The study's objective was to evaluate Zinc and Copper status among Egyptian Type 2 Diabetics and their relationship to glycemic control and micro vascular complications. Patients and methods: Cross-sectional research was conducted on A total of a hundred adult Egyptian patients of both sexes (33 males and 67 females) with T2DM, All procedures of this study were following Al-Azhar University committee regulations and standards. Results: a significant correlation at the 0.05 level between serum CU and glycemic control evidenced by HbA1c level was noticed. The glycemic control indicated by the HbA1c level and serum Zn did not substantially correlate. There was also no substantial connection between serum Cu and serum Zn on one hand and the occurrence of diabetic micro vascular complications as evident by DR and its grades on the other hand. Conclusion: The results denoting that glycemic status may affect the trace elements concentrations, also it confirms that some minerals and trace elements altered in diabetics may play a role in the development of diabetes or diabetic complications.

Keywords

diabetes; minerals; trace elements; Free radicals; Oxidative Stress

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