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Corresponding Author

Said, Ibrahim

Document Type

Original Article

Abstract

Background: Diffusion-weighted imaging (DWI) investigates the microstructure of biological tissue. The variation obtained with this approach, and the estimation of ADC values for the apparent diffusion coefficient, are helpful MRI techniques that may be utilized for non-invasive tissue assessment . Aim of Work: The goal of this research is to see how valuable both qualitative and quantitative DWI assessments are in distinguishing among spinal tumors, as well as to find a cut-off ADC value among benign and malignant tumors. Patients and Methods: Studied at the Radio-Diagnosis Department of Sayed Galal hospital, National Cancer Institute. Using 1.5T MRI unit. Sagittal T1WI, T2WI, and axial T2WI & DWI MRI sequences were acquired. Results: At least one spinal lesion of any kind was detected or suspected in at least 50 people in our study. MRI of the spine using diffusion-weighted imaging has been shown to be effective in determining whether a tumor's origin is benign or malignant. An ADC value analysis, on the other hand, was able to discriminate between benign and malignant increases in DWI signal intensity. The ADC values of cancer-infected bone marrow were higher than those of healthy bone marrow, according to our findings. The highest ADC values were found in inflamed lesions and hemangiomas. Conclusion: The standard MRI procedure for spine exams should be changed to incorporate DWI as a price alternate to the gadolinium enhanced scan, particularly in patients who are contraindicated to contrast injection.

Keywords

DWI; Vertebral lesions; Bone marrow; ADC; benign & Malignant lesions

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