Diagnostic Value of Serum Procalcitonin Level in HCV Cirrhotic Patients with Spontaneous Bacterial Peritonitis

Authors

Mahmoud Ahmed Ismail, Hepatolog Gastroenterology and Infectious diseases, faculty of medicine Al Azhar university cairo EgyptFollow
Nader Mostafa, Department of Hepatology, Gastroenterology and Infectious diseases, Faculty of Medicine, Al-Azhar University, Cairo, EgyptFollow
Islam Mawla Ammar, Department of Hepatology, Gastroenterology and Infectious diseases, Faculty of Medicine, Al-Azhar University, Cairo, EgyptFollow
Mohammed Ibrahim, Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, EgyptFollow

Corresponding Author

Ahmed Ismail, Mahmoud

Document Type

Original Article

Abstract

Background: Early diagnosis and prompt treatment of spontaneous bacterial peritonitis (SBP) due to end-stage liver disease is vital to shorten hospital stays and reduce mortality. Many studies have explored the potential usefulness of serum procalcitonin (PCT) in predicting SBP. Objective: to evaluate the overall diagnostic accuracy of PCT levels for identifying SBP due to end-stage liver disease. Patients and Methods: A prospective case control study was conducted on 60 post-HCV cirrhotic patients and 20 normal individuals (54 M and 26 F), at internal medicine department, Zagazig General Hospital. Full history, routine, physical examination and special investigations were taking. Results: The summary estimates for serum PCT in the diagnosis of SBP attributable to end stage liver disease were: sensitivity 95% and specificity 95%. Serum PCT is a relatively sensitive and specific test for the identification of SBP. However, due to the limited high-quality studies available, medical decisions should be carefully made in the context of both PCT test results and other clinical findings including diagnostic paracentesis. Conclusion: For our study we can concluded that: Serum Procalcitonin level can be used as a diagnostic test for rapid and accurate diagnosis of Spontaneous bacterial peritonitis in HCV cirrhotic patients with sensitivity and specificity about 95%.

Keywords

Diagnostic Accuracy; HCV Cirrhotic Patients; Serum Procalcitonin; Spontaneous Bacterial Peritonitis

How to Cite This Article

Ahmed Ismail, Mahmoud; Mostafa, Nader; Mawla Ammar, Islam; and Ibrahim, Mohammed (2020) "Diagnostic Value of Serum Procalcitonin Level in HCV Cirrhotic Patients with Spontaneous Bacterial Peritonitis," Al-Azhar International Medical Journal: Vol. 1: Iss. 3, Article 2.
DOI: https://doi.org/10.21608/aimj.2020.22933.1103