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Document Type

Original Article

Abstract

Background: Abnormal uterine bleeding in postmenopausal women is a common complaint in general gynecological practice. Progression and prognosis of AUB primarily relies on invasive surgery and pathology so our research aimed to evaluate the use of non-invasive procedures such as uterine artery Doppler indices and coagulation profile in detecting some underlaying causes of AUB. Aim and objectives: To evaluate the coagulation profile (PT, PTT, INR and platelete count) in women with postmenopausal bleeding in relation to 2D ultrasound endometrial thickness and uterine artery Doppler. Patients and methods: This longitudinal observational study was performed at the departments of Obstetrics and Gynecology at AL-Zahraa University hospital and El-Salam Specialized hospital and it was carried from January 2022 to September 2022 and included 80 women with postmenopausal abnormal uterine bleeding as a sample size using Transvaginal Ultrasound (Siemens Acuson NX2 Ultrasound machine). Conclusion: Coagulation profile and Transvaginal ultrasound measurement of endometrial thickness are reliable methods of screening women with postmenopausal abnormal uterine bleeding. The measurement of endometrial thickness can serve as a noninvasive screening instrument for the evaluation of AUB. In malignant conditions, Color Doppler can detect neovascularization and decreased pulsatility index and resistive index in uterine vessels. D-dimer is a basic biomarker for detecting an abnormal coagulation profile in AUB cases.

Keywords

Abnormal uterine bleeding; postmenopausal bleeding; Uterine Artery Doppler; Coagulation Profile; D-dimer

Subject Area

Obstetrics and Gynecology

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