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Document Type

Original Article

Abstract

Background: A surgical procedure known as penetrating keratoplasty (PKP) involves replacing donor tissue throughout the entire recipient corneal thickness. Good to exceptional quality donor corneal tissues are preferred by PKP surgeons because they give enough endothelial cells for a lifetime.

Objective: The aim of the study was to assess endothelial cell count one and half month after penetrating keratoplasty (PKP) by using specular microscopy. Method: It is cross-sectional, descriptive Study which done at Giza memorial institute of ophthalmic research from September 2021 to June 2022. This study WAS performed on 30 eyes of 30 patients that underwent penetrating keratoplasty. Results:Comparison of endothelial cell loss between patients according to indication showed that the loss was statistically significant higher in opacity group than KC group, where endothelial cell loss ranged from 512 to 799 cell/mm2, mean ± SD. Was 636.8 ± 79.28, and median 641 in KC group, and ranged from 502 to 1011 cell/mm2, mean ± SD. Was 759.5 ± 149.0, and median 715 in opacity group. Conclusion: Our research showed that following PKP, the loss of endothelial cells is greatly accelerated.We also noticed that a number of factors affect how quickly endothelial cells are lost following PKP, where the recipient age and the death to preservation time were positively associated with ECD loss, and higher in opacity group than KC group and not influenced by donar age and preservation to surgery time

Keywords

EVALUATION, ENDOTHELIAL CELL COUNT, CORNEAL GRAFT, PENETRATING KERATOPLASTY

Subject Area

Ophthalmology

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