Document Type
Original Article
Abstract
Background: Asthma is still a main etiology of complaining all over the world. Much indirect evidence recommends that immunoglobulin E (IgE) and Eosinophil could have an essential role in asthma irrespective of conventional atopic condition.
objective: To trace the expression of local Eosinophil (%) and local IgE in the absence of systemic IgE in asthmatic cases with nasal polyps.
Subjects and methods: 90 subjects were included and were divided into 3 groups: Group A: consists of 30 patients had non-atopic bronchial asthma and nasal polyps. Group B: consists of 30 patients with nasal polyps only. Group C: consists of 30 healthy normal candidates as controls.
Results: The mean levels of local Eosinophil (%) count and local IgE were significantly increased in group A and B in comparison with group C (P
Conclusion: Local Eosinophil (%) and local IgE showed significant elevation in patients with bronchial asthma and nasal polyps and cases with nasal polyps in comparison to controls. Moreover, Local IgE and local Eosinophil (%) were found to be positively correlated with symptoms severity.
Keywords
Asthma; Nasal Polyps; Non-atopic; IgE; Eosinophil
Subject Area
Chest, ENT, General Medicine
How to Cite This Article
Elezawey, Abdallah Mohamed Ali; Farag, Farag Khalil; Elsharkawey, Mohamed Ahmed; Eldewi, Dalia Mahmoud; and Lotfy, Abdel Wahab Mohamed
(2023)
"Tracing of Local Atopy Among Apparently Non Atopic Asthmatics with Nasal Polyps,"
Al-Azhar International Medical Journal: Vol. 4:
Iss.
7, Article 31.
DOI: https://doi.org/10.58675/2682-339X.1879
