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Document Type

Original Article

Abstract

Background:After their insertion, prosthetic valves—either mechanical or biological—have some drawbacks. There are many challenging events that lead to dysfunction of prothesis, such as formation of a thrombus or pannus, para-valvular leakage, and developing cardiac infections after the prosthesis, like endocarditis. Objective:to assess factors that are responsible for malfunction of prosthetic cardiac valves;in addition, assessment of post-operative mortality and morbidity of those patients. Patient and methods:In this prospective study, we followed up the early results of surgical intervention in 40 patients with malfunction prosthetic cardiac valves at the Cardiothoracic Surgery Department, El-Hussien Hospital, Al-Azhar University;the follow-up timespan was from March 2019 till May 2022. Results: We reported the causative eventsofprostheticvalves malfunctionas the following:Thrombus formation was reportedin 25% of the total patients included in the study, while thrombus and pannus were reported in 37.5%. Pannus only was reported in 30% of the total patients included in the study. The calculated overall mortality for patients who suffered from prosthesis’malfunction,which mandatedre-replacement of valve, was 7 out of 40 patients (17.5%). Conclusion:We concluded that the majorcomplication that leads to failure of mechanical valve prosthesisis formation of boththrombus and pannus;surgical management is associatedwithsignificantmortalityandmorbidity.Hence, better clinical outcomes can be achieved by both early diagnosis and prompt reoperation

Keywords

malfunction; heart; prosthesis.

Subject Area

Thoracic and cardiovascular surgery

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