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Document Type

Original Article

Abstract

Background: Due to the existence of its receptor in cardiomyocytes, vitamin D deficiency influences alterations in these cells. People who have low levels of 25OHD in their blood are more likely to get an acute myocardial infarction (MI).

Aim of the work: to assess the level of vitamin D (concentrations of 25-OHD in serum) in people having acute coronary syndrome (ACS) and its relationship to the extent of the condition.

Methods: This Cross-sectional work was performed on 50 individuals. Age ranged from 32 to 82 diagnosed with ACS. All patients were subjected to left ventricular function (estimated ejection fraction (EF) using either echocardiography or left ventriculography), Twelve–lead Electrocardiogram (ECG), 25-OH Vitamin D in serum.

Results: 66% of the instances were diagnosed with STEMI by the ECG. 34% of the cases were non-STEMI, 18% had anterior non-STEMI, 12% had inferior non-STEMI and 4% of them had lateral STEMI. regarding ECHO EF, it ranges between 38% and 65% while mean ECHO EF was 51.94 ± 7.03. 26% of the cases had – creatine kinase-myoglobin binding (CKMB), while 44% of them had + CKMB, 20% of them had ++ CKMB, and 10% of them had +++ CKMB. Regarding vitamin D level there was a negative medium correlation among vessels number, syntax score and vitamin D, r = -0.585, r = -0.589 respectively p-value

Conclusions: Deficiency of Vitamin D showed a higher prevalence rate among ACS patients, A medium negative correlation among vessels number, syntax score and vitamin D.

Keywords

Vitamin D; serum 25-OHD concentration; Acute Coronary Syndrome.

Subject Area

Cardiology

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