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Corresponding Author

Mohammed Mahmoud Ahmed El Desoukey

Authors ORCID

Mofeed Fawzy Mohammed Mohammed Ahmed Abdelmoaty

Document Type

Original Article

Abstract

Background: Preeclampsia etiology remains a mystery, a multitude of theories propose aberrant placental implantation and deviant trophoblastic invasion. Clinical studies examining the link between vitamin D concentrations and poor pregnancy results like preeclampsia have shown mixed findings.

Objective: To measure serum concentrations of vitamin D in pre-eclamptic gestated women and to compare them with their healthy counterparts.

Subjects and methods: After the 20th week of gestation, a prospective case control research was done on 100 gestating women: 50 gestating women with preeclampsia and 50 gestating women without preeclampsia (controls). Subjects whom were selected to assess total 25-OH vitamin D using an enzymatic immunoassay technique.

Results: Our findings showed that there was statistically substantial reduce in the median vitamin D serum concentrations of preeclampsia patients (17.47±4.86 mg/dl) compared to controls (27.15±5.94 mg/dl), (t=-8.909, P

Conclusion: When PE pregnant women were analyzed to normotensive pregnant women, plasma vitamin D concentrations were considerably lower. As a result, this research has suggested the potential of a link between maternal vitamin D insufficiency and the incidence of PE.

Keywords

Preeclampsia, vitamin D, vitamin D deficiency.

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