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Corresponding Author

El--Sherbiny, Gamal

Abstract

Aimed of the work; Assessment of the microbial species from diabetic and nondiabetic illness and their antibiotics susceptibility patterns. Patients and Methods. Two hundred urine specimens were collected from illness in a duration period extending from July 2018 to July 20119 at Badr University Hospital-Helwan, Cairo, Egypt. Samples were collecting cultivated on MacConkey, blood agar, and Sabouraud dextrose media. The microbial isolates were identified by microbiological methods. The antibiotic sensitivity was evaluated by the VITEK 2 compact automatic system and disk diffusion method. Results: Only 120 samples exhibit growth with a prevalence rate of 60%, from total samples collected. The results revealed UTIs were found to be significantly higher in diabetic illness (79%) compared to nondiabetic illness (41%). One hundred and twenty microbial species were recovered from collected urine specimens (79 from diabetic and 41 nondiabetics). Pathogenic bacteria & Candida were represented with 96 isolates (80.0 %) and 24 isolates (20.0), respectively. Among the 96 bacterial isolates, Escherichia coli constituted, Escherichia coli (72.80%), Klebsiella pneumonia (22.88%), and Staphylococcus aureus (4.16%). Meropenem, imipenem, trimethoprim/ sulphamethoxazole, and norfloxacin highly effective antibiotics against E. coli and Klebsiella pneumonia while amoxicillin, erythromycin, and vancomycin low effective. Conclusion: Diabetes disease a remarkable factor that stimulates UTIs. Higher frequency resistance to antibiotics in this study renders its indecency for empirical treatment and development of new empirical treatment.

Article Type

Original Article

Keywords

UTIs; diabetics; nondiabetics; antibiotics; resistance

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